Thrombosis Thrombocytopenia Syndrome (TTS) is a rare but serious condition associated with certain COVID-19 vaccines, particularly adenovirus vector vaccines like AstraZeneca and Johnson & Johnson’s Janssen vaccine.
What is Thrombosis Thrombocytopenia Syndrome (TTS)? TTS is characterized by blood clots (thrombosis) combined with low levels of platelets (thrombocytopenia), which are necessary for blood clotting. It often involves unusual blood clot locations, such as in the brain (cerebral venous sinus thrombosis) or abdomen.
TTS symptoms
TTS symptoms include severe or ongoing headaches, impaired vision, breathing difficulties, chest pain, leg swelling, stomach pain that doesn’t go away, easy bruising, and small blood spots under the skin that extend beyond the injection site. Even though TTS is uncommon, people who have had TTS-related vaccinations should be aware of the symptoms and seek medical assistance if they appear within a few weeks following the shot. Effective TTS management requires early detection and intervention.
“Thrombosis with thrombocytopenia syndrome, or TTS, is characterized by low platelet counts and blood clots in the brain or other regions of the body. It happens infrequently after receiving particular vaccinations and for other reasons. In particular, adenovirus vector vaccinations have not been frequently linked to this illness, according to the WHO,” Dr. Jayadevan, Co-Chairman of the Kerala-based National Indian Medical Association (IMA) Covid Task Force, informed ANI.
“While Covid vaccines have undoubtedly saved lives, reports of these extremely rare but potentially serious immune-mediated events have also been documented in reputable journals,” said Dr. Jayadevan.
AstraZeneca, the pharmaceutical behemoth, has admitted that its COVID-19 vaccination may cause Thrombosis with Thrombocytopenia Syndrome (TTS), an uncommon adverse effect. This information was reported in a story by The Telegraph.
A 2023 article on Yalemedicine.org states that a blood clot is simply a clump of blood that resembles gel. Naturally, when you cut or scrape your skin to stop bleeding, small blood clots form. But they turn deadly when they grow inside a blood vessel and impede blood flow, a condition known to cause thrombosis, which kills up to 100,000 people annually in the US. According to Robert Bona, MD, a hematologist at Yale Medicine, “Those clots typically occur in individuals who are hospitalized, bedridden, or have other medical issues related to inflammation, infection, or cancer.”
AstraZeneca acknowledges that a rare side effect of the Covishield vaccine may occur.
The Oxford-AstraZeneca COVID vaccination was sold under several brand names, such as Covishield and Vaxzevria, in different parts of the world.
The COVID-19 vaccination known as Covishield was created by the Serum Institute of India. It is based on the viral vector platform rather than the mRNA platform. This vaccine delivers the COVID-19 spike protein into human cells using a chimpanzee adenovirus that has been modified (ChAdOx1). Although the recipient cannot contract this cold virus, it can successfully direct the immune system to build defenses against viruses that are identical to it.
The World Health Organization (WHO) announced in 2023 that among recipients of COVID-19 non-replicant viral vector-based vaccinations, thrombosis with thrombocytopenia syndrome (TTS) developed as a new adverse event after immunization. This covers the COVID-19 Ad26.COV2-S vaccination from Johnson & Johnson (J&J) and the COVID-19 ChAdOx-1 vaccine from AstraZeneca.
Thrombosis Concerns about thrombocytopenia syndrome (TTS) have surfaced in relation to some COVID-19 vaccines, especially those that use adenovirus vector technology, such the ChAdOx1 vaccination from AstraZeneca and the Ad26.COV2-S vaccine from Johnson & Johnson. TTS is characterized by thrombosis, or blood clots, and thrombocytopenia, or low platelet counts. These conditions pose a major risk to health and call for immediate medical intervention.
The incidence of TTS has brought up significant issues with vaccination safety, risk assessment, and the handling of uncommon vaccine-related problems in the medical profession and among the general population. Healthcare professionals, legislators, and those getting the COVID-19 vaccine must all comprehend the nature of TTS, its symptoms, risk factors, and management techniques.
TTS: Comprehending the Situation
Thrombosis Thrombocytopenia Syndrome (TTS) is an uncommon but potentially dangerous illness marked by low platelet counts (thrombocytopenia) and blood clots (thrombosis) that occur simultaneously in the body.
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