Study Links Both Low and High Vitamin B12 Levels to Cognitive Decline in Older Adults
A recent study has found that **both lower and higher levels of vitamin B12 may be linked to cognitive issues in older adults**, even when these levels fall within the normal range. The findings, published in *Annals of Neurology*, suggest that **B12 levels may influence brain function and neurodegeneration**, prompting a reevaluation of current clinical standards.
Vitamin B12: Essential for Brain and Nerve Health**
Vitamin B12, or cobalamin, plays a crucial role in **nerve tissue development, brain function, and red blood cell production**. It is naturally found in **animal-based foods such as meat, fish, eggs, and dairy** and can also be obtained from fortified cereals, nutritional yeast, and supplements. While B12 deficiency is rare, **low or marginal levels are common**, affecting nearly **40% of Western populations**.
The **National Institutes of Health (NIH)** recommends a daily intake of **2.4 micrograms of B12 for individuals over 14 years old**. Despite this, the latest study highlights that even within normal B12 ranges, **variations in levels could impact cognitive health**.
B12 Levels and Cognitive Decline
The study analyzed **healthy older adults** and found:
– **Lower B12 levels were linked to slower processing speed**, potentially due to impaired nerve insulation.
– **Higher B12 levels were associated with increased biomarkers of neurodegeneration**, raising concerns about excess intake.
Dr. Clifford Segil, a neurologist at **Providence Saint John’s Health Center in Santa Monica, CA**, who was not involved in the study, noted that the findings challenge existing medical practices. **“This study suggests rethinking what should be considered a low B12 level in clinical settings. I often treat patients with ‘normal’ B12 levels who still experience memory loss,”** he said.
With dementia and cognitive decline affecting millions globally, experts emphasize the importance of **monitoring B12 levels carefully**. The study calls for further research into the **optimal B12 range for cognitive health** and whether current guidelines need adjustments.
